Medicinal Mushroom Alcohol Extract vs. Hot Water Extract

By Dr. Markho Rafael

For two millennia, medicinal mushrooms have been mainstream in Asia. Now, America is taking notice and interest is rapidly "mushrooming." With the sprouting of this new industry follows issues of ethical quality claims between competing brands.

This information applies to all species of medicinal mushrooms. For practical purposes, this article will focus on the most popular medicinal mushroom species, red reishi (Ganoderma lucidum), over which the most intense battle of conflicting claims is being fought.

The first and perhaps obvious caution is to stay away from cheap mass-produced brands of medicinal mushrooms that may only contain dried and pulverized mushrooms, in which case the medicinal compounds are still inaccessible behind the mushrooms' cell walls.

Then there are the real therapeutic grade red reishi brands, which are produced with much more care. But even here there are big differences between brands. Each claims to be the best, of course, because they want to sell their product. So lets set the facts straight and be independently informed consumers.

Following are the three primary ways of creating reishi extracts. Each method yields different medicinal compounds, all of which are shown in scientific studies to have important properties.

1. Water (Hot) Extraction (polysaccharides, etc.)

2. Alcohol Extraction (triterpenoids, sterols)

3. Fermented (arabinoxylanes, etc.)

The most important hot water extracted compounds are the polysaccharides. Studies have shown them to possess strong anti-tumor properties, help boost immune system and be powerful antioxidants. [1]

The alcohol soluble compounds are mainly triterpenoids, a large group of related compounds. Scientific studies suggest they help stabilize cholesterol, blood pressure and clotting. Most importantly, they are the anti-inflammatory compounds so critical to many of reishi's suggested uses, including arthritis, allergies and asthma. [1]

And then there are the new and unique medicinal compounds that get created when reishi is fermented. These "secondary metabolites" have their own therapeutic properties, different from the first two groups, including anti-tumor, immune support and blood-sugar balance. [2]

Since this article is not intended to elevate any one brand over another, no brand names will be mentioned. Nevertheless, the author does know of two highly reputed brands (American and Japanese) that claim only hot water extracted red reishi is of any value and that alcohol extracts are useless.

They do that, of course, because they wish to sell their products. However, there is no scientific validity to those claims. All three extraction methods listed above yield important medicinal compounds.

When looking for the best reishi extract, find one that uses at least the first two extraction methods in combination: Hot Water and Alcohol Extraction. Even better may be a brand that includes all three methods listed.

An additional point to keep in mind is the form the reishi comes in. Reishi that dissolves completely in a water-based liquid such as coffee probably only contains reishi from hot water extraction. As a substitute for regular coffee, this would be a superb health-choice. However, it will not contain the water-insoluble triterpenoids so valued for their anti-inflammatory properties.

On the other hand, alcohol tinctures can actually contain both water soluble polysaccharides and alcohol soluble triterpenoids. The way you know is that the polysaccharides will fall out of solution because of the alcohol, and will make the tincture cloudy. That's alright though; you just need to shake before you take. Capsules and tablets may be one or the other or both. The only way to know is ask the manufacturer or read their information.

[1] Boh B, Berovic M, Zhang J, Zhi-Bin L. "Ganoderma lucidum and its pharmaceutically active compounds." Biotechnol Annu Rev. 2007;13:265-301.

[2] Tang YJ, Zhang W, Zhong JJ. "Performance analyses of a pH-shift and DOT-shift integrated fed-batch fermentation process for the production of ganoderic acid and Ganoderma polysaccharides by medicinal mushroom Ganoderma lucidum." Bioresour Technol. 2009 Mar;100(5):1852-9. - 30286

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